Reviews & Analysis

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  • In this Perspective, Teichmann and colleagues present ongoing efforts from consortia of the Human Cell Atlas to harmonize and integrate data sources into a reference cell ontology and the contributions of cell ontologies to discovery.

    • David Osumi-Sutherland
    • Chuan Xu
    • Sarah A. Teichmann
    Perspective
  • In this Perspective, Börner et al. discuss initiatives by 16 consortia to construct a Human Reference Atlas (HRA) comprising reference organs linked to tables that name major anatomical structures, cell types, plus biomarkers (ASCT+B) and present examples of HRA usage.

    • Katy Börner
    • Sarah A. Teichmann
    • Griffin Weber
    Perspective
  • In this Perspective, Fuxreiter and Vendruscolo discuss the fundamental nature of the droplet and amyloid states of proteins, the regulatory mechanisms controlling their formation, and the cellular functions associated with these condensed states.

    • Monika Fuxreiter
    • Michele Vendruscolo
    Perspective