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Artistic rendition of hyperbranched amplicons created by multiple-displacement amplification. Gole et al. uniformly amplify the DNA of single cells in nanoliter wells, enabling copynumber variants to be detected in primary human neurons (p 1126). Credit: Kun Zhang
Moves to give biosimilars nonproprietary names different from brand products are more than a wrangle about words—they could mean biosimilars arrive stillborn to the market.
There are many advantages to becoming a company advisor, but academics should think carefully about the legal and personal implications before accepting a seat on the board.
When applied in large scale to electronic medical record data, the PheWAS approach replicates GWAS associations and reveals potentially new pleiotropic associations.
Arrays of nanoliter wells reduce bias in single-cell genome sequencing, allowing copy number changes in one cell to be detected at unprecedented resolution.
A fusion protein comprising a TALE DNA-targeting domain and the 5-methylcytosine hydroxylase TET1 enables investigation of the function of specific DNA methylation events.
The current academic culture needs to change its mission, which is narrowly focused on training PhDs to be the next generation of academic tenure-track scientists.