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Two studies show direct conversion of mouse embryonic fibroblasts to oligodendrocyte progenitor cells capable of generating myelinating oligodendrocytes.
Two studies show direct conversion of mouse embryonic fibroblasts to oligodendrocyte progenitor cells capable of generating myelinating oligodendrocytes.
A computational pipeline identifies genetic variants that affect transcriptional responses to stimuli, and uses this information to refine molecular circuits.
A CRISPR-Cas system is harnessed to introduce template-driven mutations in S. pneumoniae and E. coli at high efficiency without requiring selectable markers.
A draft sequence of the staple crop kabuli chickpea, together with resequencing and analysis of 90 additional lines from 10 countries, provides a resource for breeders.
Whole-genome bisulfite sequencing reveals that global reprogramming of the epigenome occurs during the maturation of tomato fruits, potentially identifying new targets for breeders.