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Simultaneous recordings from hundreds of grid cells in rats, combined with topological data analysis, show that network activity in grid cells resides on a toroidal manifold that is invariant across environments and brain states.
Geochemical analyses correlating the stratum that overlies the sediments containing the Omo fossils with material from a volcanic eruption suggest that these fossils (the oldest known modern human fossils in eastern Africa) are over 200,000 years old.
Different racial/ethnic populations and income groups are found to have been exposed to different levels of air pollution in the USA during the years 2000 to 2016.
Data on de novo mutations in Arabidopsis thaliana reveal that mutations do not occur randomly; instead, epigenome-associated mutation bias reduces the occurrence of deleterious mutations.
A crossbar array of magnetic memory to execute analogue in-memory computing has been developed, and performs image classification and facial detection at low power.
A global assessment shows that increases in the number of wet days and extreme daily rainfall adversely affect economic growth, particularly in high-income nations and via the services and manufacturing sectors.
A chromatin accessibility atlas of 240,919 cells in the adult and developing Drosophila brain reveals 95,000 enhancers, which are integrated in cell-type specific enhancer gene regulatory networks and decoded into combinations of functional transcription factor binding sites using deep learning.
An analysis of Zeeman measurements reveals that the reduction of magnetic flux relative to mass, which is necessary for star formation, seems to have occurred earlier than previously thought.
Cryo-electron microscopy structures of DNA-dependent protein kinase catalytic subunit bound to ATPγS and four inhibitors (wortmannin, NU7441, AZD7648 and M3814) provide molecular details and insights useful for drug design.
Methicillin-resistant strains of Staphylococcus aureus appeared in European hedgehogs in the pre-antibiotic era as a co-evolutionary adaptation to antibiotic-producing dermatophytes and have spread within the local hedgehog populations and between hedgehogs and secondary hosts.
X-ray diffraction experiments indicate that the depression of the Earth’s 660-kilometre seismic discontinuity beneath cold subduction zones is caused by a phase transition from akimotoite to bridgmanite, leading to slab stagnation.
High-dimensional datasets derived from time-resolved live imaging of leukocytes in mice were used to identify leukocyte identities and dynamic neutrophil states with high cellular resolution.
Using intracranial electrocorticography and a series of motor tasks, a speech planning network that is central to natural language generation during social interaction is identified.
The discovery and synthesis of a colistin congener provide a promising clinical lead against mcr-1-encoding colistin-resistant pathogens, which are responsible for an increasing number of deaths from antibiotic-resistant infections.
Multiple high-precision measurement campaigns at CERN of the antiproton-to-proton charge-to-mass ratio—to a precision of 16 parts per trillion—in a cryogenic multi-Penning trap offer no evidence of charge–parity–time violation, and set stringent limits on the clock-weak-equivalence principle.
Spontaneous crystallization of atoms occurs in a rotating ultracold Bose–Einstein condensate occupying the lowest Landau level, behaviour that is related to a quantum hydrodynamic instability driven by shear forces.
