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Francis S. Collins and Lawrence A. Tabak discuss initiatives that the US National Institutes of Health is exploring to restore the self-correcting nature of preclinical research.
Edward B. Barbier and colleagues call for governance and funds for deep-sea reserves and the restoration of ecosystems damaged by commercial interests.
Separate ethics courses are not enough, argues Erin A. Cech. Understanding the public-welfare impacts of science and engineering is a core professional skill.
Gross domestic product is a misleading measure of national success. Countries should act now to embrace new metrics, urge Robert Costanza and colleagues.
Practical, interdisciplinary ways of working forged during the Second World War had a lasting impact on a generation of physicists and their findings, says David Kaiser.