Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain
the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in
Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles
and JavaScript.
Silicon photonic nanocavities based on surface forces and conventional lithography and etching are developed, demonstrating pioneering technology that integrates atomic dimensions with the scalability of planar semiconductors.
A new discovery strategy, ‘reverse metabolomics’, facilitates high-throughput matching of mass spectrometry spectra in public untargeted metabolomics datasets, and a proof-of-concept experiment identified an association between microbial bile amidates and inflammatory bowel disease.
Authentic hypoblast cells created from naive human pluripotent stem cells (hPSCs) spontaneously assemble with naive hPSCs to form a three-dimensional bilaminar structure (bilaminoids) with a pro-amniotic-like cavity.
Integration of multiomics data with functional analysis of pancreatic tissues from individuals with early-stage type 2 diabetes indicates that the genetic risk converges on RFX6, which regulates chromatin architecture at multiple risk loci.
A plasma set-up consisting of a pair of carbon-fibre-tip-enhanced electrodes enables the generation of a uniform, ultra-high temperature and stable plasma (up to 8,000 K) at atmospheric pressure using a combination of vertically oriented long and short carbon fibres.
After loss of MSL2, a class of dosage-sensitive genes transitions from biallelic to monoallelic expression, whereby one allele remains active, retaining active histone modifications and transcription factor binding, and the other allele is silenced, exhibiting loss of promoter–enhancer contacts and the acquisition of DNA methylation.
An autonomous laboratory, the A-Lab, is presented that combines computations, literature data, machine learning and active learning, which discovered and synthesized 41 novel compounds from a set of 58 targets after 17 days of operation.
We provide a modified strategy for the on-surface synthesis of cyclocarbons with 10 or 14 carbon atoms that provides a route for characterizing annular carbon allotropes.
Whole-genome alignment of 239 primate species reveals noncoding regulatory elements that are under selective constraint in primates but not in other placental mammals, that are enriched for variants that affect human gene expression and complex traits in diseases.
Observations of six transiting planets around the bright nearby star HD 110067 show that they follow a chain of resonant orbits, with three of the planets inferring the presence of large hydrogen-dominated atmospheres.
A model of sediment flux from the land to the oceans over the Phanerozoic eon explains differences in the fossil records of marine animal genera and land plant genera.
On a 51-ion quantum simulator, we investigate locality of entanglement Hamiltonians for a Heisenberg chain, demonstrating Bisognano–Wichmann predictions of quantum field theory applied to lattice many-body systems, and observe the transition from area- to volume-law scaling of entanglement entropies.
The redox behaviour of pyridinium electrolytes under representative flow battery conditions is investigated, offering insights into air tolerance of batteries containing these electrolytes while providing a universal physico-chemical descriptor of their reversibility.
We gathered genetic data for 1,763 individuals from 147 populations across 14 African countries, and 12 Late Iron Age individuals, to trace the expansion of Bantu-speaking peoples over the past 6,000 years.
A protocol using large-scale training of graph networks enables high-throughput discovery of novel stable structures and led to the identification of 2.2 million crystal structures, of which 381,000 are newly discovered stable materials.
Results from 316 Bombus terrestris colonies at 106 agricultural sites across eight European countries find pesticides in bumble bee pollen to be associated with reduced colony performance, especially in areas of intensive agriculture.
The accuracy of eukaryotic ribosome translocation relies on eukaryote-specific elements of the 80S ribosome, elongation factor 2 and transfer RNAs, all of which contribute to the maintenance of the messenger RNA reading frame.
There is extreme socioeconomic segregation in large US cities, arising from a greater choice of differentiated spaces targeted to specific socioeconomic groups, which can be countered by positioning city hubs (such as shopping centres) to bridge diverse neighbourhoods.
