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Organic light-emitting devices containing radical emitters can achieve an efficiency of 27 per cent at deep-red and infrared wavelengths based on the excitation of spin doublets, rather than singlet or triplet states.
Drosophila melanogaster are attracted to CO2 when in an active, foraging state but experience aversion to CO2 at low-activity levels, whereas they are attracted to ethanol in all behavioural states.
Ikzf2, which encodes the transcription factor Helios, is identified as a crucial regulator of gene expression in maturing cochlear outer hair cells, and overexpression of Ikzf2 in inner hair cells induces prestin expression and electromotility.
Distinct transcriptional programs are activated during different stages of apoptotic cell engulfment, including a unique program of genes coding for solute carrier proteins and enzymes in the glycolytic pathway.
From 1901 to 2015, missing and disappeared glaciers produced a rise in sea level that may enable the historical budget for global-mean sea-level rise to be closed without recourse to an undiscovered physical process.
TIC236 is an inner-membrane protein that binds to the outer-membrane channel TOC75 to create a long, stable bridge that enables the transport of proteins into chloroplasts.
Mannose reduces the growth of tumour cells by impairing the metabolism of glucose, and enhances cell death when used in combination with conventional chemotherapy.
New World hantaviruses—which cause a severe human respiratory disease—use surface glycoproteins to bind to the human protocadherin-1 protein and enter endothelial cells in vitro; depleting protocadherin-1 in Syrian golden hamsters largely protects against disease.
Strains of methicillin-resistant Staphylococcus aureus use a prophage-encoded glycosyltransferase to alter the glycosylation of their wall teichoic acid and thereby evade antibody-mediated immune responses.
In zebrafish embryogenesis, nascent haematopoietic stem and progenitor cells (HSPCs), homing to a vascular niche for retention, are ushered by patrolling and guiding macrophages through integrin-mediated cell-cell recognition.
Levallois stone-tool technology found at the Guanyindong Cave site in southwest China was dated to approximately 170,000–80,000 years ago, which is much earlier than previously thought.
Modelling the contribution of urbanization to the impacts associated with hurricane Harvey in August 2017 shows that urbanization worsens rainfall and flooding.
An immunoprecipitation-based protocol is developed to analyse DNA methylation in small quantities of circulating cell-free DNA, and can detect and classify cancers in plasma samples from several tumour types.
Neanderthals and Upper Palaeolithic modern humans exhibit similar overall incidences of cranial trauma that are higher for males of both taxa; however, there are species-specific, age-related variations in trauma prevalence.
Hippocampal activity during a period of sleep after memory encoding is crucial for forming long-term memories in rats, even for types of memory considered not to be hippocampus-dependent.
Seismic images of Earth’s crust and uppermost mantle around the Mariana trench show widespread serpentinization, suggesting that much more water is subducted than previously thought.
Introduction of a suicide gene together with a linked cell-division gene to generate a safe-cell system enables the selective elimination of proliferating cells after cell transplantation in mouse models of cell therapy.
Analysis of 20 years of observations of Barnard’s star from seven facilities reveals a signal with a period of 233 days that is indicative of a companion planet.
Mice with whole-body or liver-specific deletion of Atg7 release circulating arginase I and have reduced levels of serum arginine, which impairs the growth of allografted arginine-auxotrophic tumours.