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Mechanochemistry is the science of inducing a chemical reaction through the application of mechanical force. This Perspective focuses on combining traditional mechanochemistry with different energy inputs — heat, light, sound or electrical impulses — to advance mechanochemical synthesis.
Endergonic photocatalysis enables the catalytic and atom-economic synthesis of products with higher free energies than reactants. This Perspective highlights current progress in endergonic photocatalysis by summarizing the energetics of these reactions and points out the industrial potential of such processes.
Studies employing machine-learning (ML) tools in the chemical sciences often report their evaluations in a heterogeneous way. The evaluation guidelines provided in this Perspective should enable more rigorous ML reporting.
