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Immunofluorescence staining showing nuclei (blue), and CX3CR1-GFP+ microglia (green) in newborn brains expressing Type-I interferon receptor 1 (red). Microglia of offspring that were exposed during pregnancy to elevated Type-I interferon are perturbed and exhibit increased sensitivity to postnatal stress, which is accompanied by behavioral manifestations reminiscent of various neuropsychiatric disorders. For more information see the article by Ben-Yehuda et al. on pages 1050-1067.