Letter to the Editor in 2022

AI-empowered integrative structural characterization of m⁶A methyltransferase complex

• Xuhui Yan
• Kai Pei
• Ping Yin

Molecular recognition of itch-associated neuropeptides by bombesin receptors

• Changyao Li
• Youwei Xu
• Wanchao Yin

Cryo-EM structure of the type III-E CRISPR-Cas effector gRAMP in complex with TPR-CHAT

• Shuo Wang
• Minghui Guo
• Zhiwei Huang

scNanoATAC-seq: a long-read single-cell ATAC sequencing method to detect chromatin accessibility and genetic variants simultaneously within an individual cell

• Yuqiong Hu
• Zhenhuan Jiang
• Fuchou Tang

Deep learning-based rapid generation of broadly reactive antibodies against SARS-CoV-2 and its Omicron variant

• Hantao Lou
• Jianqing Zheng
• Xuetao Cao

Creation of artificial karyotypes in mice reveals robustness of genome organization

• Xiaoyu Merlin Zhang
• Meng Yan
• Jinsong Li

mRNA vaccines expressing homo-prototype/Omicron and hetero-chimeric RBD-dimers against SARS-CoV-2

• Yuxuan Han
• Yaling An
• George F. Gao

Omicron-specific mRNA vaccine elicits potent immune responses in mice, hamsters, and nonhuman primates

• Yi Wu
• Yanqiong Shen
• Yucai Wang

A broadly neutralizing antibody against SARS-CoV-2 Omicron variant infection exhibiting a novel trimer dimer conformation in spike protein binding

• Yingdan Wang
• Wuqiang Zhan
• Jinghe Huang

Structure of human NTCP reveals the basis of recognition and sodium-driven transport of bile salts into the liver

• Hongtao Liu
• Rossitza N. Irobalieva
• Kaspar P. Locher

Safety and superior immunogenicity of heterologous boosting with an RBD-based SARS-CoV-2 mRNA vaccine in Chinese adults

• Xiaoqiang Liu
• Yuhua Li
• Cheng-Feng Qin

Disease profile and plasma neutralizing activity of post-vaccination Omicron BA.1 infection in Tianjin, China: a retrospective study

• Hong Zheng
• Yunlong Cao
• Zhongyang Shen

Selection and structural bases of potent broadly neutralizing antibodies from 3-dose vaccinees that are highly effective against diverse SARS-CoV-2 variants, including Omicron sublineages

• Lei Wang
• Wangjun Fu
• Xiangxi Wang

Structures of the endogenous peptide- and selective non-peptide agonist-bound SSTR2 signaling complexes

• Li-Nan Chen
• Wei-Wei Wang
• Chunyou Mao

Retractosomes: small extracellular vesicles generated from broken-off retraction fibers

• Yizheng Wang
• Shuaixin Gao
• Li Yu

Structural basis for pore blockade of human voltage-gated calcium channel Ca_v1.3 by motion sickness drug cinnarizine

• Xia Yao
• Shuai Gao
• Nieng Yan

Generic amyloid fibrillation of TMEM106B in patient with Parkinson’s disease dementia and normal elders

• Yun Fan
• Qinyue Zhao
• Dan Li

piRNA 3′ uridylation facilitates the assembly of MIWI/piRNA complex for efficient target regulation in mouse male germ cells

• Mao-Zhou Zhao
• Di-Hang Lin
• Mo-Fang Liu

Enhanced trimeric ACE2 exhibits potent prophylactic and therapeutic efficacy against the SARS-CoV-2 Delta and Omicron variants in vivo

• Mengjiao Li
• Zi-Wei Ye
• Bobo Dang

Structural insights into the SARS-CoV-2 Omicron RBD-ACE2 interaction

• Jun Lan
• Xinheng He
• Xinquan Wang