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Special Feature on Epstein-Barr Virus (EBV)
It has been 50 years since Michael Anthony Epstein and Yvonne Barr discovered Epstein-Barr Virus (EBV) particles in cell lines cultured from tumor tissue from a Burkitt lymphoma. Since the initial discovery of the virus, more than 20,000 scientific papers on the characteristics, functions and oncogenic mechanisms of viral genes, the spectrum of EBV-associated diseases, and treatment of patients have been published. Experimental & Molecular Medicine contains six review articles that provide an overview of our current understanding of Epstein-Barr virology and oncogenesis and of EBV-associated neoplasm.
Editorial
EBV and human cancer Open
Young-Hyeh Ko
Experimental & Molecular Medicine 47: e130; Published online, 23 January 2015; doi:10.1038/emm.2014.109
Reviews
Epstein–Barr virus latent genes Open
Myung-Soo Kang and Elliott Kieff
Experimental & Molecular Medicine 47: e131; Published online, 23 January 2015; doi:10.1038/emm.2014.84
EBV-driven B-cell lymphoproliferative disorders: from biology, classification and differential diagnosis to clinical management Open
Chi Young Ok, Ling Li and Ken H Young
Experimental & Molecular Medicine 47: e132; Published online, 23 January 2015; doi:10.1038/emm.2014.82
Epstein–Barr virus-positive T/NK-cell lymphoproliferative disorders Open
Qingqing Cai, Kailin Chen and Ken H Young
Experimental & Molecular Medicine 47: e133; Published online, 23 January 2015; doi:10.1038/emm.2014.105
Genomic assays for Epstein–Barr virus-positive gastric adenocarcinoma Open
Margaret L Gulley
Experimental & Molecular Medicine 47: e134; Published online, 23 January 2015; doi:10.1038/emm.2014.93
Modeling EBV infection and pathogenesis in new-generation humanized mice Open
Shigeyoshi Fujiwara, Ken-Ichi Imadome and Masami Takei
Experimental & Molecular Medicine 47: e135; Published online, 23 January 2015; doi:10.1038/emm.2014.88
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