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Early life is a risky time for infectious diseases. Here, we highlight research on how alveolar macrophages, intestinal CD8s, and intestinal epithelial derived anti-microbial molecules may be impaired in neonates and contribute to disease.
The female reproductive tract must balance mucosal immunity to pathogens with essential life-sustaining support during pregnancy. These highlighted articles delve into tissue-resident memory, MAIT, and NK cell responses in the female reproductive tract.
The airway epithelium is the first line of defense and can influence the course of the local immune response in the respiratory tract. Recent work shows the heterogeneity of the epithelium, and how they contribute to allergic inflammation and bacterial infections.