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"Despite the availability of multiple pharmacotherapies and the known preventative capacities of life-style modification, hypertension remains a highly prevalent disorder worldwide. Indeed, high blood pressure (BP) is estimated to result in approximately half of the global burden of cardiovascular disease. This group of Reviews highlights the current thinking on best methods of BP measurement, appropriate BP targets in patients with hypertension, challenges in patient compliance to prescribed therapies, the very latest advances in antihypertensive treatments—including fixed-dose combinations and device therapy—and the management of elderly patients with this hypertension.
Because of the global impact of this disorder, and because of its modifiable nature, Nature Reviews Cardiology and the World Heart Federation are holding a joint session on 'Hypertension in 2012' at the World Heart Federation's 2012 World Congress of Cardiology in Dubai, UAE. The session will cover community-wide strategies for prevention of hypertension, BP measurement and targets, the latest advances in antihypertensive therapies, and management of hypertension in the elderly. Review articles that accompany two talks in this session (written by the commissioned speakers) are included in this May 2012 focus issue of Nature Reviews Cardiology.
Efforts to improve health-care quality and efficiency will fail if patients with chronic disease do not adhere to medications and healthy lifestyles. A novel, psychological approach is to change behavior using 'affect' and 'affirmations'. We explore this strategy's potential, when added to the existing arsenal of interventions, to improve adherence.
Elevated blood pressure (BP) is probably the most-important, modifiable risk factor for cardiovascular disease. Dr. Ruilope discusses current controversies and challenges in the treatment of patients with arterial hypertension, including the validity of office BP measurements, appropriateness of BP targets, use of combination therapy, and patient compliance.
Hypertension is the most prevalent controllable disease in the adult population of the developed world. Although various effective treatments are available, the development of novel therapies is still required. The authors review key advances in pharmacological and nonpharmacological therapies for hypertension in 2010–2011 and comment on possible future developments.
Hypertension is a highly prevalent modifiable risk factor for cardiovascular disease, which is particularly common among older adults. The elderly represent an important, although often overlooked, group of patients for whom assessment and treatment of hypertension requires special consideration. Comorbidities, multiple drug regimens, and potential causes of secondary hypertension can all affect the management of these individuals. Drs Pimenta and Oparil review the pathophysiology of hypertension in the elderly and how best to assess and treat these patients.