Genetics and Genomics in 2012

Melatonin induces transcriptional regulation of Bim by FoxO3a in HepG2 cells

• S Carbajo-Pescador
• C Steinmetz
• S Strand

MicroRNA profiling of peripheral nerve sheath tumours identifies miR-29c as a tumour suppressor gene involved in tumour progression

• N Presneau
• M Eskandarpour
• A M Flanagan

EGFR pathway biomarkers in erlotinib-treated patients with advanced pancreatic cancer: translational results from the randomised, crossover phase 3 trial AIO-PK0104

• S Boeck
• A Jung
• V Heinemann

Analysis of gene alterations of mitochondrial DNA D-loop regions to determine breast cancer clonality

• S Masuda
• T Kadowaki
• R Y Osamura

An inherited NBN mutation is associated with poor prognosis prostate cancer

• C Cybulski
• D Wokołorczyk
• J Lubiński

The incidence of pancreatic cancer in BRCA1 and BRCA2 mutation carriers

• J Iqbal
• A Ragone
• S A Narod

KRAS gene amplification and overexpression but not mutation associates with aggressive and metastatic endometrial cancer

• E Birkeland
• E Wik
• H B Salvesen

Basal core promoter mutation is associated with progression to cirrhosis rather than hepatocellular carcinoma in chronic hepatitis B virus infection

• C-M Chu
• C-C Lin
• Y-F Liaw

Frequency of mutations in mismatch repair genes in a population-based study of women with ovarian cancer

• T Pal
• M R Akbari
• S A Narod

Exon-level expression analyses identify MYCN and NTRK1 as major determinants of alternative exon usage and robustly predict primary neuroblastoma outcome

• A Schramm
• B Schowe
• J H Schulte

Patterns of genomic loss of heterozygosity predict homologous recombination repair defects in epithelial ovarian cancer

• V Abkevich
• K M Timms
• J S Lanchbury

The FOXM1-PLK1 axis is commonly upregulated in oesophageal adenocarcinoma

• M Dibb
• N Han
• A D Sharrocks

Segmental chromosomal alterations have prognostic impact in neuroblastoma: a report from the INRG project

• G Schleiermacher
• V Mosseri
• A D J Pearson

Analysis of molecular intra-patient variation and delineation of a prognostic 12-gene signature in non-muscle invasive bladder cancer; technology transfer from microarrays to PCR

• L Dyrskjøt
• T Reinert
• T F Ørntoft

Mismatch repair deficiency: a temozolomide resistance factor in medulloblastoma cell lines that is uncommon in primary medulloblastoma tumours

• A O von Bueren
• M D Bacolod
• S Rutkowski

The collagen prolyl hydroxylases are novel transcriptionally silenced genes in lymphoma

• E Hatzimichael
• C Lo Nigro
• T Crook

Genomic Grade Index predicts postoperative clinical outcome of GIST

• F Bertucci
• P Finetti
• D Birnbaum

The TERT variant rs2736100 is associated with colorectal cancer risk

• B Kinnersley
• G Migliorini
• R S Houlston

A gene expression signature distinguishes normal tissues of sporadic and radiation-induced papillary thyroid carcinomas

• G Dom
• M Tarabichi
• C Maenhaut

Site-specific CpG methylation in the CCAAT/enhancer binding protein delta (CEBPδ) CpG island in breast cancer is associated with metastatic relapse

• C Palmieri
• M Monteverde
• T Crook