The eye and the brain are both recognized as immune-privileged sites. Research now indicates that responses in the eye mirror those in the central nervous system (CNS), offering major implications for the treatment of CNS cancers and infections.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 digital issues and online access to articles
$119.00 per year
only $9.92 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Medawar, P. B. Br. J. Exp. Pathol. 29, 58–69 (1948).
Streilein, J. W. Nat. Rev. Immunol. 3, 879–89 (2003).
Yin, X. et al. Nature https://doi.org/10.1038/s41586-024-07130-8 (2024).
Louveau, A. et al. Nature 523, 337–341 (2015).
Rustenhoven, J. et al. Cell 184, 1000–1016.e27 (2021).
Wang, X. et al. Sci. Transl. Med 12, eaaw3210 (2020).
Rosin, B., Banin, E. & Sahel, J.-A. Cold Spring Harb. Perspect. Med. 11, a041301 (2023).
Yang, P., Mustafi, D. & Pepple, K. L. Cold Spring Harb. Perspect. Med. 14, a041305 (2024).
Kolabas, Z. I. et al. Cell 186, 3706–3725.e29 (2023).
Mazzitelli, J. A. et al. Nat. Neurosci. 26, 2052–2062 (2023).
Author information
Authors and Affiliations
Corresponding authors
Ethics declarations
Competing interests
J.K. is a co-founder of Rho Bio. J.T.W. declares no competing interests.
Rights and permissions
About this article
Cite this article
Walsh, J.T., Kipnis, J. An immunological window to the brain. Nat Cardiovasc Res 3, 405–406 (2024). https://doi.org/10.1038/s44161-024-00457-5
Published:
Issue Date:
DOI: https://doi.org/10.1038/s44161-024-00457-5