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Neuroscience

Linking neuropsychiatric disease to neuronal metabolism

Stress is an important risk factor for neuropsychiatric disorders such as major depression, but the underlying biological mechanisms remain largely unclear. A recent study has revealed a mechanism that regulates neuronal metabolism and mitochondrial function, and thereby drives stress susceptibility and disease outcomes.

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Fig. 1: Stress susceptibility through mitochondrial neuronal metabolism.

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Correspondence to Mathias V. Schmidt.

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Schmidt, M.V. Linking neuropsychiatric disease to neuronal metabolism. Nat Metab 5, 2041–2042 (2023). https://doi.org/10.1038/s42255-023-00929-1

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