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Gastroenterology

A multi-omic trip through the human gut

Most of human microbiome research has focused on analysing faecal samples, which represent the final stop of the digestive journey. Two recent articles use a novel sampling approach to capture luminal content at different points during digestion and reveal that the analysis of faecal samples tells only a fraction of the story.

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Fig. 1: Sampling approach.

References

  1. Shalon, D. et al. Nature https://doi.org/10.1038/s41586-023-05989-7 (2023).

  2. Folz, J. et al. Nat. Metab. https://doi.org/10.1038/s42255-023-00777-z (2023).

  3. Evans, D.F., Pye, G., Bramley, R., Clark, A.G., Dyson, T.J., Hardcastle, J.D. 1988. Gut 29, 1035–1041 (1988).

  4. Devkota, S. et al. Nature 487, 104–108 (2012).

  5. da Silva, R.R., Dorrestein, P.C. & Quinn, R.A. Proc. Natl Acad. Sci. 112, 12549–12550 (2015).

  6. Hofmann, A.F. & Hagey L.R. J. Lipid Res. 55, 1553–1595 (2014).

  7. Quinn, R.A. Nature 579, 123–129 (2020).

  8. Lucas, L.N. mSystems 6, e0080521 (2021).

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Correspondence to Robert A. Quinn.

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Quinn, R.A., Martin, C. & Guzior, D.V. A multi-omic trip through the human gut. Nat Metab 5, 720–721 (2023). https://doi.org/10.1038/s42255-023-00773-3

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