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MITOCHONDRIAL BIOLOGY

Cracking the enigma of mitochondrial-DNA variants and cancer

Nature Metabolism volume 2, pages 221–222 (2020)Cite this article

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A recent study by Yuan et al., published in Nature Genetics, demonstrates multidimensional molecular alterations in mitochondrial DNA in human cancers and provides an online catalogue of mitochondrial genomes in many cancer types.

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Fig. 1: The landscape of mtDNA mutations in cancer.

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Authors and Affiliations

  1. Department of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, Cambridge, UK

    Wei Wei & Patrick F. Chinnery

  2. Medical Research Council Mitochondrial Biology Unit, University of Cambridge, Cambridge, UK

    Wei Wei & Patrick F. Chinnery

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  1. Wei Wei
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  2. Patrick F. Chinnery
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Correspondence to Patrick F. Chinnery.

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The authors declare no competing interests.

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Wei, W., Chinnery, P.F. Cracking the enigma of mitochondrial-DNA variants and cancer. Nat Metab 2, 221–222 (2020). https://doi.org/10.1038/s42255-020-0180-2

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