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The chicken embryo as an in vivo experimental model for drug testing: Advantages and limitations

Lab Animal volume 50, pages 138–139 (2021)Cite this article

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Alternatives for in vivo assays for drug testing have been proposed to solve open issues, such as costs, ethical, and logistical problems. One option is the chicken embryo. Here, we discuss its use as an experimental model for drug testing as well as limitations that researchers who want to work with the model should consider.

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Fig. 1: Main inoculation routes in a 10 embryonic incubation day (EID) chicken embryo.

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Acknowledgements

To Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES), Fundação de Amparo a Pesquisa do Estado de Minas Gerais (FAPEMIG) and Conselho Nacional de Desenvolvimento Científico e Tecnológico” (CNPq) that support our work. To Laudo Laboratório company (especially to Dr. Marcio Botrel, Gustavo Mazer Ferraz and Rogério de Avelar Ferraz) who always support us with Technical experience. To Hy Line and VALO BioMedia Companies that support us with eggs in our research.

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Authors and Affiliations

  1. School of Veterinary Medicine, Federal University of Uberlandia, Uberlândia, Brazil

    Belchiolina Beatriz Fonseca

  2. Rodents Animal Facility Complex of Federal University of Uberlândia, Uberlândia, Brazil

    Murilo Vieira da Silva

  3. Institute of Biotechnology, Federal University of Uberlandia, Uberlândia, Brazil

    Lígia Nunes de Morais Ribeiro

Authors
  1. Belchiolina Beatriz Fonseca
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  2. Murilo Vieira da Silva
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  3. Lígia Nunes de Morais Ribeiro
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Correspondence to Belchiolina Beatriz Fonseca.

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Fonseca, B.B., da Silva, M.V. & de Morais Ribeiro, L.N. The chicken embryo as an in vivo experimental model for drug testing: Advantages and limitations. Lab Anim 50, 138–139 (2021). https://doi.org/10.1038/s41684-021-00774-3

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