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TFH cell responses endure in human lymph nodes after vaccination

Nature Immunology volume 25, pages 1510–1512 (2024)Cite this article

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Longitudinal sampling of human lymph nodes using fine-needle aspiration after influenza or SARS-CoV-2 vaccination reveals substantial durability and transcriptional reprogramming of follicular helper T cells over time.

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Fig. 1: Durability and plasticity of human dLN TFH cells after vaccination.

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Authors and Affiliations

  1. Transplantation Research Center, Division of Renal Medicine, Department of Medicine, Brigham and Women’s Hospital, Boston, MA, USA

    Cody S. Nelson & Peter T. Sage

  2. Division of Allergy and Clinical Immunology, Department of Medicine, Brigham and Women’s Hospital, Boston, MA, USA

    Cody S. Nelson

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  1. Cody S. Nelson
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  2. Peter T. Sage
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Correspondence to Peter T. Sage.

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The authors declare no competing interests.

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Nelson, C.S., Sage, P.T. TFH cell responses endure in human lymph nodes after vaccination. Nat Immunol 25, 1510–1512 (2024). https://doi.org/10.1038/s41590-024-01935-5

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