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KARR-seq maps higher-order RNA structures and RNA–RNA interactions across the transcriptome

Mapping higher-order RNA structures and intermolecular RNA–RNA interactions throughout the transcriptome is critical for understanding RNA functions. We developed KARR-seq, a chemical-assisted RNA proximity capture and sequencing technology that enables sensitive and accurate detection of the RNA structurome and functional RNA–RNA interactions.

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Fig. 1: Mapping cellular RNA–RNA interactions by KARR-seq.

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This is a summary of: Wu, T. et al. KARR-seq reveals cellular higher-order RNA structures and RNA–RNA interactions. Nat. Biotechnol. https://doi.org/10.1038/s41587-023-02109-8 (2024)

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KARR-seq maps higher-order RNA structures and RNA–RNA interactions across the transcriptome. Nat Biotechnol (2024). https://doi.org/10.1038/s41587-023-02110-1

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