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STRUCTURAL BIOLOGY

Type VI secretion system baseplate

Bacteria employ a specialized weapon known as the type VI secretion system to defend themselves from competing organisms. A new study reveals the molecular architecture of the type VI secretion system and highlights conserved mechanistic similarities with contractile phage tails.

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Fig. 1: Structural resemblance of the T6SS to phage T4.

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Correspondence to Karen L. Maxwell.

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Davidson, A.R., Maxwell, K.L. Type VI secretion system baseplate. Nat Microbiol 3, 1330–1331 (2018). https://doi.org/10.1038/s41564-018-0311-7

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