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Sensing fungi at the oral epithelium

The mechanisms involved in controlling Candida albicans at mucosal sites are not fully understood. Recent work identifies the EphA2 on epithelial cells as a fungal β-glucan receptor that is critical for mediating protective immunity during oral candidiasis.

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Fig. 1: The role of EphA2 in the detection of Candida albicans in the oral epithelium.

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Correspondence to Ivy M. Dambuza or Gordon D. Brown.

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Dambuza, I.M., Brown, G.D. Sensing fungi at the oral epithelium. Nat Microbiol 3, 4–5 (2018). https://doi.org/10.1038/s41564-017-0086-2

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