Quantitatively studying the partitioning of biomolecules and reaction equilibria in cellular systems is an enormous challenge. Now, a multiphase coacervate model system provides insight into this complex biological problem, illustrating how coexisting phases influence RNA partitioning and duplex dissociation.
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Wu, S., Tian, L. Multiphase model membraneless organelles. Nat. Chem. 14, 1095–1097 (2022). https://doi.org/10.1038/s41557-022-01043-7
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DOI: https://doi.org/10.1038/s41557-022-01043-7