By regulating the condensation of the molecular transport machinery coat protein complex II (COPII), manganese ions contribute to the regulation of lipoprotein secretion and thereby the circulating lipid levels.
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References
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This is a summary of: Wang, X. et al. Manganese regulation of COPII condensation controls circulating lipid homeostasis. Nat. Cell Biol. https://doi.org/10.1038/s41556-023-01260-3 (2023).
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Manganese controls lipoprotein secretion via biomolecular condensation. Nat Cell Biol 25, 1732–1733 (2023). https://doi.org/10.1038/s41556-023-01300-y
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DOI: https://doi.org/10.1038/s41556-023-01300-y