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Salvage hematopoietic cell transplantation for children with acute myeloid leukemia relapsed after first transplantation: a Japanese national registry study

Bone Marrow Transplantation (2024)Cite this article

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Fig. 1: Transplant outcomes by remission status at second hematopoietic cell transplantation and prognostic poor score.

Data availability

The original data may be available from the corresponding author upon reasonable request and with permission of the Japan Society for Transplantation and Cellular Therapy and Japanese Data Center for Hematopoietic Cell Transplantation.

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Acknowledgements

We would like to thank all the participating patients and doctors involved in the Transplant Registry Unified Management Program in collaboration with the Japanese Data Center for Hematopoietic Cell Transplantation, Japan Society for Transplantation and Cellular Therapy, Japan Society for Pediatric Hematology and Oncology, Japan Marrow Donor Program, Cord Blood Banks and Japanese Red Cross Society.

Author information

Authors and Affiliations

  1. Children’s Cancer Center, National Center for Child Health and Development, Tokyo, Japan

    Hirotoshi Sakaguchi, Kimikazu Matsumoto & Daisuke Tomizawa

  2. Department of Pediatrics, Shiga University of Medical Science, Otsu, Japan

    Takashi Taga

  3. Department of Pediatrics, Okayama University Hospital, Okayama, Japan

    Hisashi Ishida

  4. Department of Hematology and Oncology, Children’s Medical Center, Japanese Red Cross Aichi Medical Center Nagoya First Hospital, Nagoya, Japan

    Asahito Hama & Nao Yoshida

  5. Department of Pediatrics, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan

    Yasuhiro Okamoto

  6. Department of Pediatric Oncology, Fukushima Medical University Hospital, Fukushima, Japan

    Hideki Sano

  7. Department of Hematology/Oncology, Osaka Women’s and Children’s Hospital, Izumi, Japan

    Maho Sato

  8. Department of Pediatrics, Kyushu University Hospital, Fukuoka, Japan

    Yuhki Koga

  9. Department of Hematology/Oncology, Saitama Children’s Medical Center, Saitama, Japan

    Katsuyoshi Koh & Yuichi Mitani

  10. Division of Hematology/Oncology, Kanagawa Children’s Medical Center, Yokohama, Japan

    Fuminori Iwasaki

  11. Department of Pediatrics, Hokkaido University Hospital, Sapporo, Japan

    Yuko Cho

  12. Department of Pediatric Hematology/Oncology, Osaka City General Hospital, Osaka, Japan

    Keiko Okada

  13. Department of Pediatrics, The University of Tokyo Hospital, Tokyo, Japan

    Kentaro Watanabe

  14. Department of Pediatric and Adolescent Hematology/Oncology, Niigata Cancer Center Hospital, Niigata, Japan

    Akihiro Watanabe

  15. Department of Hematology and Oncology, Center of Childhood Cancer, Hyogo Prefectural Kobe Children’s Hospital, Kobe, Japan

    Daiichiro Hasegawa

  16. Department of Pediatrics, National Hospital Organization Kyushu Cancer Center, Fukuoka, Japan

    Maiko Noguchi

  17. Department of Pediatrics, Osaka International Cancer Institute, Osaka, Japan

    Yoshiko Hashii

  18. Japanese Data Center for Hematopoietic Cell Transplantation, Nagakute, Japan

    Ken Tabuchi

  19. Shiga General Hospital, Moriyama, Japan

    Soichi Adachi

  20. Department of Pediatrics, Mie University Graduate School of Medicine, Tsu, Japan

    Shotaro Iwamoto

  21. Department of Pediatrics, Jichi Medical University, Tochigi, Japan

    Yuta Kawahara & Akira Shimada

  22. Department of Pediatrics, Toho University Omori Medical Center, Tokyo, Japan

    Yasuko Kojima

  23. Department of Pediatrics, Yokohama City University Graduate School of Medicine, Yokohama, Japan

    Shinichi Tsujimoto

  24. Department of Pediatrics, Osaka University Graduate School of Medicine, Suita, Japan

    Takako Miyamura

  25. Department of Pediatrics, Tokai University School of Medicine, Isehara, Japan

    Shohei Yamamoto

  26. Department of Pediatrics, Nagoya University Graduate School of Medicine, Nagoya, Japan

    Ayako Yamamori

  27. Department of Pediatric Hematology and Oncology Research, Research Institute, National Center for Child Health and Development, Tokyo, Japan

    Masanori Yoshida

Authors
  1. Hirotoshi Sakaguchi
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  2. Takashi Taga
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  3. Hisashi Ishida
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  4. Asahito Hama
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  5. Yasuhiro Okamoto
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  6. Hideki Sano
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  7. Maho Sato
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  8. Yuhki Koga
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  9. Katsuyoshi Koh
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  10. Fuminori Iwasaki
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  11. Nao Yoshida
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  12. Yuko Cho
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  13. Keiko Okada
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  14. Kentaro Watanabe
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  15. Akihiro Watanabe
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  16. Daiichiro Hasegawa
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  17. Maiko Noguchi
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  18. Yoshiko Hashii
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  19. Kimikazu Matsumoto
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  20. Ken Tabuchi
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Consortia

Pediatric Acute Myeloid Leukemia Working Group of Japanese Society for Transplantation and Cellular Therapy

  • Hirotoshi Sakaguchi
  • , Takashi Taga
  • , Hisashi Ishida
  • , Asahito Hama
  • , Yasuhiro Okamoto
  • , Daisuke Tomizawa
  • , Yuichi Mitani
  • , Fuminori Iwasaki
  • , Daiichiro Hasegawa
  • , Yoshiko Hashii
  • , Ken Tabuchi
  • , Soichi Adachi
  • , Shotaro Iwamoto
  • , Yuta Kawahara
  • , Akira Shimada
  • , Yasuko Kojima
  • , Shinichi Tsujimoto
  • , Takako Miyamura
  • , Shohei Yamamoto
  • , Ayako Yamamori
  •  & Masanori Yoshida

Contributions

HSak, TT, HI, AH, and YO designed the study, analyzed the data, and wrote the manuscript. HSan, MS, YK, KK, FI, NY, YC, KO, KW, AW, DH, and MN contributed to the registration. YH, KM, and KT are responsible for data management. All authors discussed and approved the manuscript.

Corresponding author

Correspondence to Hirotoshi Sakaguchi.

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Competing interests

The authors declare that they have no competing interests. This study was partially supported by a grant from the National Centre for Child Health and Development (2024B-15).

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Sakaguchi, H., Taga, T., Ishida, H. et al. Salvage hematopoietic cell transplantation for children with acute myeloid leukemia relapsed after first transplantation: a Japanese national registry study. Bone Marrow Transplant (2024). https://doi.org/10.1038/s41409-024-02396-y

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  • DOI: https://doi.org/10.1038/s41409-024-02396-y

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