Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Meeting Report
  • Published:

Intracellular RNA sorting, transport and localization

RNA localization and translational control are crucial for cellular fine-tuning of gene expression in space and time. A recent meeting in Tucson, Arizona pointed out mechanisms conserved across different species and cell types that contribute to the establishment of cell polarity and cell migration. Furthermore, it is becoming increasingly clear that these post-transcriptional control processes are relevant for various diseases.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

References

  1. St Johnston, D. Nat. Rev. Mol. Cell Biol. 6, 363–375 (2005).

    Article  CAS  Google Scholar 

  2. Steward, O. & Levy, W.B. J. Neurosci. 2, 284–289 (1982).

    Article  CAS  Google Scholar 

  3. Kuhl, D. & Skehel, P. Curr. Opin. Neurobiol. 8, 600–606 (1998).

    Article  CAS  Google Scholar 

  4. Gonsalvez, G.B., Urbinati, C.R. & Long, R.M. Biol. Cell. 97, 75–86 (2005).

    Article  CAS  Google Scholar 

  5. Farina, K.L., Hüttelmaier, S., Musunuru, K., Darnell, R. & Singer, R.H. J. Cell Biol. 160, 77–87 (2003).

    Article  CAS  Google Scholar 

  6. Zhang, H.L. et al. Neuron 31, 261–275 (2001).

    Article  CAS  Google Scholar 

  7. Betley, J.N. et al. Curr. Biol. 14, 219–224 (2004).

    Article  CAS  Google Scholar 

  8. Yoon, Y.J. & Mowry, K.L. Development 131, 3035–3045 (2004).

    Article  CAS  Google Scholar 

  9. Palacios, I.M. & St Johnston, D. Development 129, 5473–5485 (2002).

    Article  CAS  Google Scholar 

  10. Fusco, D. et al. Curr. Biol. 13, 161–167 (2003).

    Article  CAS  Google Scholar 

  11. Delanoue, R. & Davis, I. Cell 122, 97–106 (2005).

    Article  CAS  Google Scholar 

  12. Kloc, M. & Etkin, L.D. J. Cell Sci. 118, 269–282 (2005).

    Article  CAS  Google Scholar 

  13. Kloc, M. et al. Development 132, 3445–3457 (2005).

    Article  CAS  Google Scholar 

  14. Nakamura, A., Sato, K. & Hanyu-Nakamura, K. Dev. Cell 6, 69–78 (2004).

    Article  CAS  Google Scholar 

  15. Cho, P.F. et al. Cell 121, 411–423 (2005).

    Article  CAS  Google Scholar 

  16. Alarcon, J.M. et al. Learn. Mem. 11, 318–327 (2004).

    Article  Google Scholar 

  17. Huang, Y.S. & Richter, J.D. Curr. Opin. Cell Biol. 16, 308–313 (2004).

    Article  Google Scholar 

  18. Hüttelmaier et al., Nature in the press (2005).

    Google Scholar 

  19. Sheth, U. & Parker, R. Science 300, 805–808 (2003).

    Article  CAS  Google Scholar 

  20. Teixeira, D., Sheth, U., Valencia-Sanchez, M.A., Brengues, M. & Parker, R. RNA 11, 371–382 (2005).

    Article  CAS  Google Scholar 

  21. Liu, J., Valencia-Sanchez, M.A., Hannon, G.J. & Parker, R. Nat. Cell Biol. 7, 719–723 (2005).

    Article  CAS  Google Scholar 

  22. Ainger, K. et al. J. Cell Biol. 123, 431–441 (1993).

    Article  CAS  Google Scholar 

  23. Kosturko, L.D., Maggipinto, M.J., D'Sa, C., Carson, J.H. & Barbarese, E. Mol. Biol. Cell 16, 1938–1947 (2005).

    Article  CAS  Google Scholar 

Download references

Acknowledgements

We would like to thank to A. Ephrussi, I. Palacios and J.C. Lopez for thoughtful comments and for critical reading of the manuscript.

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Jansen, RP., Kiebler, M. Intracellular RNA sorting, transport and localization. Nat Struct Mol Biol 12, 826–829 (2005). https://doi.org/10.1038/nsmb1005-826

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nsmb1005-826

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing