An important aspect of eukaryotic gene expression is the efficient integration of transcription, pre-mRNA processing and nuclear export. A new study demonstrates that pre-mRNA transcript continuity is an essential component for maintaining productive coupling of transcription and RNA processing events.
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Klaue, Y., Hertel, K. Dangerous play—splitting the message may leave you empty handed. Nat Struct Mol Biol 16, 907–908 (2009). https://doi.org/10.1038/nsmb0909-907
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DOI: https://doi.org/10.1038/nsmb0909-907