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Stroke

Stroke prevention—time to say goodbye to the ABCD2 score?

The ABCD2 score was developed to triage patients with transient ischaemic attack according to the risk of experiencing a stroke in the next few hours or days. However, a new systematic review and meta-analysis on the ABCD2 score gives us considerable cause to rethink its value for clinical situations.

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Correspondence to Hans-Christoph Diener.

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Competing interests

H.-C.D. has received honoraria for participation in clinical trials, contribution to advisory boards or oral presentations from: Abbott, Allergan, AstraZeneca, Bayer Vital, BMS, Boehringer Ingelheim, CoAxia, Corimmun, Covidien, Daiichi-Sankyo, D-Pharm, Fresenius, GlaxoSmithKline, Janssen-Cilag, Johnson & Johnson, Knoll, Lilly, MSD, Medtronic, MindFrame, Neurobiological Technologies, Novartis, Novo-Nordisk, Paion, Parke-Davis, Pfizer, Sanofi-Aventis, Schering-Plough, Servier, Solvay, St. Jude, Syngis, Talecris, Thrombogenics, WebMD Global, Wyeth and Yamanouchi. Financial support for his research projects was provided by AstraZeneca, GlaxoSmithKline, Boehringer Ingelheim, Lundbeck, Novartis, Janssen-Cilag, Sanofi-Aventis, Syngis and Talecris. He has no ownership interest and does not own stocks in any pharmaceutical company. Within the past year, H.-C.D. has served as an editor for Aktuelle Neurologie, Arzneimitteltherapie, Kopfschmerznews, Stroke News and the Treatment Guidelines of the German Neurological Society, as co-editor of Cephalalgia, and on the editorial boards of The Lancet Neurology, Stroke, European Neurology and Cerebrovascular Disorders. B.F. has received honoraria from Sanofi and Bayer HealthCare.

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Diener, HC., Frank, B. Stroke prevention—time to say goodbye to the ABCD2 score?. Nat Rev Neurol 11, 552–553 (2015). https://doi.org/10.1038/nrneurol.2015.156

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