Visual hallucinations are common in patients with dementia with Lewy bodies (DLB), and can also be present in Alzheimer disease (AD). Voxel-based morphometry in 78 patients with AD, half of whom experienced hallucinations, detected specific regions of grey and white matter atrophy associated with hallucinations; the right anterior insula was of core importance. Autopsy of four patients who had experienced hallucinations revealed combined AD and DLB pathology.
References
Blanc, F. et al. Right anterior insula: core region of hallucinations in cognitive neurodegenerative diseases. PLoS ONE 9, e114774 (2014)
Rights and permissions
About this article
Cite this article
Visual hallucinations in neurodegenerative disease are associated with volume loss in the right anterior insula. Nat Rev Neurol 11, 4 (2015). https://doi.org/10.1038/nrneurol.2014.249
Published:
Issue Date:
DOI: https://doi.org/10.1038/nrneurol.2014.249