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Migraine

New US guidelines for preventive treatment of migraine

In April 2012, the American Academy of Neurology and the American Headache Society issued new guidelines on preventive treatment for episodic migraine. Although the guidelines provide valuable information regarding drug efficacy, they do not address the equally important issue of adverse events.

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References

  1. Lipton, R. B. et al. Migraine prevalence, disease burden, and the need for preventive therapy. Neurology 68, 343–349 (2007).

    Article  CAS  PubMed  Google Scholar 

  2. Silberstein, S. D. et al. Evidence-based guideline update: Pharmacologic treatment for episodic migraine prevention in adults. Report of the Quality Standards Subcommittee of the American Academy of Neurology and the American Headache Society. Neurology 78, 1337–1345 (2012).

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  3. Holland, S. et al. Evidence-based guideline update: NSAIDs and other complementary treatments for episodic migraine prevention in adults. Report of the Quality Standards Subcommittee of the American Academy of Neurology and the American Headache Society. Neurology 78, 1346–1353 (2012).

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  4. Evers, S. et al. EFNS guideline on the drug treatment of migraine—revised report of an EFNS task force. Eur. J. Neurol. 16, 968–981 (2009).

    Article  CAS  PubMed  Google Scholar 

  5. Editor's note to authors and readers: levels of evidence coming to Neurology®. Neurology®[online], (2009).

  6. Shaygannejad, V. et al. Comparison of the effect of topiramate and sodium valproate in migraine prevention: a randomized blinded crossover study. Headache 46, 642–648 (2006).

    Article  PubMed  Google Scholar 

  7. Tfelt-Hansen, P. et al. Guidelines for controlled trials of drugs in migraine: third edition. A guide for investigators. Cephalalgia 32, 6–38 (2012).

    Article  PubMed  Google Scholar 

  8. Schellenberg, R., Lichtenthal, A., Wöhling, H., Graf, C. & Brixius, K. Nebivolol and metoprolol for treating migraine: an advance on β-blocker treatment? Headache 48, 118–125 (2008).

    PubMed  Google Scholar 

  9. Linde, K. & Rossnagel, K. Propranolol for migraine prophylaxis. Cochrane Database of Systematic Reviews, Issue 2. Art. No.: CD003225. http://dx.doi.org/10.1002/14651858.CD003225.pub2.

  10. Jackson, J. L. et al. Tricyclic antidepressants and headaches: systematic review and meta-analysis. BMJ 341, c5222 (2010).

    Article  PubMed Central  PubMed  Google Scholar 

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Correspondence to Peer C. Tfelt-Hansen.

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Tfelt-Hansen, P., Hougaard, A. New US guidelines for preventive treatment of migraine. Nat Rev Neurol 8, 419–421 (2012). https://doi.org/10.1038/nrneurol.2012.115

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