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Stroke

Sedation and anesthesia during endovascular stroke therapy

A large, retrospective study indicates that in patients with acute ischemic stroke, endovascular interventions performed under conscious sedation carry a lower risk of poor neurological outcome and mortality than those performed under general anesthetic. Owing to a number of potential confounding factors, however, the results must be interpreted with caution.

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Figure 1: Use of the Penumbra Stroke System to treat acute ischemic stroke.

References

  1. Saver, J. L. Time is brain—quantified. Stroke 37, 263–266 (2006).

    Article  Google Scholar 

  2. Hacke, W. et al. Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke. N. Engl. J. Med. 359, 1317–1329 (2008).

    Article  CAS  Google Scholar 

  3. Meyers, P. M. et al. Performance and training standards for endovascular ischemic stroke treatment. AJNR Am. J. Neuroradiol. 31, E8–E11 (2010).

    Article  CAS  Google Scholar 

  4. Meyers, P. M. et al. Indications for the performance of intracranial endovascular neurointerventional procedures: a scientific statement from the American Heart Association Council on Cardiovascular Radiology and Intervention, Stroke Council, Council on Cardiovascular Surgery and Anesthesia, Interdisciplinary Council on Peripheral Vascular Disease, and Interdisciplinary Council on Quality of Care and Outcomes Research. Circulation 119, 2235–2249 (2009).

    Article  Google Scholar 

  5. Abou-Chebl, A. et al. Conscious sedation versus general anesthesia during endovascular therapy for acute anterior circulation stroke: preliminary results from a retrospective, multicenter study. Stroke 41, 1175–1179 (2010).

    Article  CAS  Google Scholar 

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Correspondence to Philip M. Meyers.

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The authors declare no competing financial interests.

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Meyers, P., Heyer, E. Sedation and anesthesia during endovascular stroke therapy. Nat Rev Neurol 6, 474–475 (2010). https://doi.org/10.1038/nrneurol.2010.110

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  • DOI: https://doi.org/10.1038/nrneurol.2010.110

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