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Epilepsy

Is localization-related epilepsy a progressive disorder? Maybe...

Nature Reviews Neurology volume 5, pages 356–357 (2009)Cite this article

The issue of whether progressive brain injury occurs in pharmacoresistant epilepsy remains important and controversial. A combined longitudinal and cross-sectional MRI study, in which an automated method was used to measure cortical thickness, has demonstrated accelerated brain atrophy in patients with chronic epilepsy.

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Authors and Affiliations

  1. New York University Comprehensive Epilepsy Center, New York, NY, USA

    Ruben Kuzniecky, Thomas Thesen & Orrin Devinsky

Authors
  1. Ruben Kuzniecky
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  2. Thomas Thesen
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  3. Orrin Devinsky
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Correspondence to Ruben Kuzniecky.

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The authors declare no competing financial interests.

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Kuzniecky, R., Thesen, T. & Devinsky, O. Is localization-related epilepsy a progressive disorder? Maybe.... Nat Rev Neurol 5, 356–357 (2009). https://doi.org/10.1038/nrneurol.2009.82

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