A new population-based cohort study in patients with type 2 diabetes mellitus has found that systolic blood pressure below the level currently recommended by hypertension guidelines is associated with a lower risk of cardiovascular events than the present threshold. However, whether blood pressure goals should be lowered remains contentious.
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References
James, P. A. et al. 2014 evidence-based guideline for the management of high BP in adults: report from the panel members appointed to the Eighth Joint National Committee (JNC 8). JAMA 311, 507–520 (2014).
Cushman, W. C. et al. Effects of intensive blood-pressure control in type 2 diabetes mellitus. N. Engl. J. Med. 362, 1575–1585 (2010).
McBrien, K. et al. Intensive and standard blood pressure targets in patients with type 2 diabetes mellitus: systematic review and meta-analysis. Arch. Intern. Med. 172, 1296–1303 (2012).
Adler, A. I. et al. Association of systolic BP with macrovascular and microvascular complications of type 2 diabetes (UKPDS 36): prospective observational study. BMJ 321, 412–419 (2000).
Margolis, K. L. et al. Outcomes of combined CV risk factor management strategies in type 2 diabetes: the ACCORD randomized trial. Diabetes Care 37, 1721–1728 (2014).
Emdin, C. A. et al. Blood pressure lowering in type 2 diabetes: a systematic review and meta-analysis. JAMA 313, 603–615 (2015).
Xie, X. et al. Effects of intensive BP lowering on CV and renal outcomes: updated systematic review and meta-analysis. Lancet 387, 435–443 (2016).
Ettehad, D. et al. Blood pressure lowering for prevention of CV disease and death: a systematic review and meta-analysis. Lancet 387, 957–967 (2016).
Adamsson Eryd, S. et al. Blood pressure and complications in individuals with type 2 diabetes and no previous cardiovascular disease: national population based cohort study. BMJ 354, i4070 (2016).
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Dojki, F., Bakris, G. Blood pressure goals in T2DM — time for a rethink?. Nat Rev Endocrinol 12, 629–630 (2016). https://doi.org/10.1038/nrendo.2016.163
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DOI: https://doi.org/10.1038/nrendo.2016.163