Optogenetic activation of a distinct, inhibitory pathway that connects the bed nucleus of the stria terminalis with the lateral hypothalamus leads to voracious eating in mice. This study adds yet another piece to the brain-feeding-circuit puzzle and makes use of a functional circuit-mapping technique that enables interrogation of neuronal connectivity in an unprecedented way.
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Hess, M., Brüning, J. The need to eat—overruling the homeostatic control of feeding. Nat Rev Endocrinol 10, 5–6 (2014). https://doi.org/10.1038/nrendo.2013.235
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DOI: https://doi.org/10.1038/nrendo.2013.235