True resistant hypertension is relatively frequent, yet effective treatment is often difficult to identify. In a new study, de Souza and colleagues demonstrate the potent blood pressure lowering effect of low-dose spironolactone in patients with evident resistant hypertension. This finding should have broad clinical implications in the effective management of a notoriously challenging condition.
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Williams, J. Spironolactone and resistant hypertension. Nat Rev Endocrinol 6, 248–250 (2010). https://doi.org/10.1038/nrendo.2010.26
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DOI: https://doi.org/10.1038/nrendo.2010.26
