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●Uninhibited antibiotic target discovery via chemical genetics. Poole, K. Nature Biotechnology December (2004)
A News and Views article about a new way to identify the bacterial targets and resistance mechanisms of novel antimicrobials.
●A series of articles on anti-infectives.Nature Reviews Microbiology December (2004)
Articles include:
●Epidemiological interpretation of antibiotic resistance studies — what are we missing? Schwaber, M. J., De-Medina, T. & Carmeli, Y.
●Antibiotic resistance: a view from the prescriber. Finch, R. G.
●The life and times of ivermectin — a success story. Ömura, S. & Crump, A.
●Antisense, siRNA, and the role of Toll-like receptors. Agrawal, S. & Kandimalla, E. R. Nature Biotechnology December (2004)
●Putting the opium in poppy to sleep. Memelink, J. Nature Biotechnology December (2004)
●Transporter of a malaria catastrophe. Wellems, T. E. Nature Medicine November (2004)
Knowledge of the mechanisms of amantadine, normally used to treat influenza, could lead to the development of new treatments for malaria.
●Treating cancer's kinase 'addiction'. Baselga, J. & Arribas, J. Nature Medicine November (2004)
●Recombinant protein therapeutics: success rates, market trends and values to 2010. Pavlou, A. K. & Reichert, J. Nature Biotechnology December (2004)
●The articles listed below are published in Nature Reviews Cancer (December 2004) to form a joint Focus on Kinases in cancer that includes articles in this issue of Nature Reviews Drug Discovery.
●Regulation of the cytoskeleton: an oncogenic function for CDK inhibitors? Besson, A., Assoian, R. K. & Roberts, J. M.
●Targeting the mitogen-activated protein kinase cascade to treat cancer. Sebolt-Leopold, J. S. & Herrera, R.
●Aurora-kinase inhibitors as anticancer agents. Keen, N. & Taylor, S.
●Gefitinib — a novel targeted approach to treating cancer. Herbst, R. S., Fukuoka, M. & Baselga, J.
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Reviews and comment from the nature publishing group. Nat Rev Drug Discov 3, 1063 (2004). https://doi.org/10.1038/nrd1602
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DOI: https://doi.org/10.1038/nrd1602