Mechanical chest compression with cardiac defibrillation does not improve 4 h survival compared with manual cardiopulmonary resuscitation (CPR) in patients with out-of-hospital cardiac arrest. The randomized LINC trial was conducted in the Netherlands, Sweden, and the UK, and involved 2,589 patients who underwent CPR with the mechanical LUCAS® Chest Compression System (Jolife AB, Sweden / Physio-Control, Inc., USA) or manual CPR as directed by European guidelines. Survival at 4 h after cardiac arrest was similar in the mechanical and manual CPR groups (23.6% and 23.7%, respectively). No differences were noted in survival at 1 or 6 months between the two interventions. Neurological outcome among survivors was good in both groups (cerebral performance category score 1 or 2 in 99% of patients in the mechanical CPR group, and 94% in the manual CPR group).
References
Rubertsson, S. et al. Mechanical chest compressions and simultaneous defibrillation vs conventional cardiopulmonary resuscitation in out-of-hospital cardiac arrest: the LINC randomized trial. JAMA 10.1001/jama.2013.282538
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Mechanical CPR with defibrillation does not improve outcomes in out-of-hospital cardiac arrest. Nat Rev Cardiol 11, 64 (2014). https://doi.org/10.1038/nrcardio.2013.198
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DOI: https://doi.org/10.1038/nrcardio.2013.198