Abstract
Genotypic causes of a phenotypic trait are typically determined via randomized controlled intervention experiments. Such experiments are often prohibitive with respect to durations and costs. We therefore consider inferring stable rankings of genes, according to their causal effects on a phenotype, from observational data only. Our method allows for efficient design and prioritization of future experiments, and due to its generality it is useable for a broad spectrum of applications.
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Stekhoven, D., Hennig, L., Sveinbjörnsson, G. et al. Causal Stability Ranking. Nat Prec (2011). https://doi.org/10.1038/npre.2011.6716.1
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DOI: https://doi.org/10.1038/npre.2011.6716.1