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Sounding out photons

Photoacoustic imaging, using laser light to stimulate the emission of ultrasonic waves from tissue inside the human body, potentially offers a route to far deeper imaging than possible with conventional optical techniques, reports Duncan Graham-Rowe.

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Figure 1: Schematic of a photoacoustic system for imaging the brain of small animals.
Figure 2: In vivo functional photoacoustic image of the cerebral haemodynamic changes (shown in colour) in response to whisker stimulations acquired non-invasively in a small animal, where the morphology of blood vessels is shown in grey scale.
Figure 3: In vivo photoacoustic image of blood vessels including single capillaries in a small animal, acquired non-invasively with an optical-resolution photoacoustic microscope.
Figure 4: In vivo photoacoustic image of a melanoma and the surrounding blood vessels in a small animal acquired non-invasively with a 50-MHz photoacoustic microscope.

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Graham-Rowe, D. Sounding out photons. Nature Photon 3, 123–125 (2009). https://doi.org/10.1038/nphoton.2009.7

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  • DOI: https://doi.org/10.1038/nphoton.2009.7

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