Why are some neurons selectively targeted for death in neurodegenerative diseases? A recent paper combines genetics in the fruit fly and mouse to uncover mechanisms underlying the vulnerability of Purkinje cells in spinocerebellar ataxia-1.
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Khurana, V., Fulga, T. & Feany, M. Senseless makes sense for spinocerebellar ataxia-1. Nat Neurosci 8, 1422–1424 (2005). https://doi.org/10.1038/nn1105-1422
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DOI: https://doi.org/10.1038/nn1105-1422
