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Adolescent dopamine slows spine maturation

Nature Neuroscience volume 16, pages 1514–1516 (2013)Cite this article

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A study now identifies an unexpected function of the D2 dopamine receptor in synapse maturation during a critical period in mice. The findings may have implications for the onset of schizophrenia in humans.

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Figure 1: D2R signaling prevents spine maturation during adolescence.

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Authors and Affiliations

  1. Institute of Molecular Medicine and Genetics, Medical College of Georgia, Georgia Regents University, Augusta, Georgia, USA

    Dong-Min Yin, Wen-Cheng Xiong & Lin Mei

  2. Wen-Cheng Xiong and Lin Mei are also in the Department of Neurology, Medical College of Georgia, Georgia Regents University, and at the Charlie Norwood Veterans Affairs Medical Center, Augusta, Georgia, USA.,

    Wen-Cheng Xiong & Lin Mei

Authors
  1. Dong-Min Yin
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  2. Wen-Cheng Xiong
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  3. Lin Mei
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Correspondence to Lin Mei.

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Yin, DM., Xiong, WC. & Mei, L. Adolescent dopamine slows spine maturation. Nat Neurosci 16, 1514–1516 (2013). https://doi.org/10.1038/nn.3558

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