A report in this issue of Nature Neuroscience demonstrates that stress in infancy leading to altered cortisol levels in childhood culminates in vulnerability to dysregulated affect in adolescent girls by biasing the functional dynamics of core neural regions mediating the generation and regulation of emotional responsiveness.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
Influences of prenatal and postnatal maternal depression on amygdala volume and microstructure in young children
Translational Psychiatry Open Access 25 April 2017
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Green, J.G. et al. Arch. Gen. Psychiatry 67, 113–123 (2010).
McEwen, B.S. & Gianaros, P.J. Ann. NY Acad. Sci. 1186, 190–222 (2010).
Tottenham, N. & Sheridan, M.A. Front. Hum. Neurosci. 3, 68 (2009).
Czéh, B., Perez-Cruz, C., Fuchs, E. & Flugge, G. Behav. Brain Res. 190, 1–13 (2008).
Kim, M.J. et al. Behav. Brain Res. 223, 403–410 (2011).
Urry, H.L. et al. J. Neurosci. 26, 4415–4425 (2006).
Johnstone, T., van Reekum, C.M., Urry, H.L., Kalin, N.H. & Davidson, R.J. J. Neurosci. 27, 8877–8884 (2007).
Burghy, C.A. et al. Nat. Neurosci. 15, 1736–1741 (2012).
Raichle, M.E. J. Neurosci. 29, 12729–12734 (2009).
Giedd, J.N. et al. J. Comp. Neurol. 366, 223–230 (1996).
Spiteri, T. et al. Behav. Brain Res. 210, 211–220 (2010).
Oyola, M.G. et al. Endocrinology 153, 837–846 (2012).
Edelmann, M.N. & Auger, A.P. Brain Behav. Immun. 25, 1299–1304 (2011).
Zeidan, M.A. et al. Biol. Psychiatry 70, 920–927 (2011).
Weaver, I.C. et al. Nat. Neurosci. 7, 847–854 (2004).
Author information
Authors and Affiliations
Corresponding authors
Ethics declarations
Competing interests
The authors declare no competing financial interests.
Rights and permissions
About this article
Cite this article
Bogdan, R., Hariri, A. Neural embedding of stress reactivity. Nat Neurosci 15, 1605–1607 (2012). https://doi.org/10.1038/nn.3270
Published:
Issue Date:
DOI: https://doi.org/10.1038/nn.3270
This article is cited by
-
Influences of prenatal and postnatal maternal depression on amygdala volume and microstructure in young children
Translational Psychiatry (2017)
-
Genetic Moderation of Stress Effects on Corticolimbic Circuitry
Neuropsychopharmacology (2016)
-
Toward Understanding How Early-Life Stress Reprograms Cognitive and Emotional Brain Networks
Neuropsychopharmacology (2016)