Two approaches to serially enrich protein post-translational modifications allow the detection of multiple modifications in a single biological sample using mass spectrometry.
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Webb, K., Bennett, E. Eavesdropping on PTM cross-talk through serial enrichment. Nat Methods 10, 620–621 (2013). https://doi.org/10.1038/nmeth.2526
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DOI: https://doi.org/10.1038/nmeth.2526