Not many other genomes are as well-studied as that of Saccharomyces cerevisiae; nonetheless, information on genomic variation in the species is scarce. Dunn et al. created a microarray platform, containing probes from S. cerevisiae and six other Saccharomyces species, to probe this diversity. They then collected 83 S. cerevisiae strains from different industrial and natural habitats and performed array comparative genomic hybridization. Almost all strains showed hybridization between strains and distribution of copy-number variation indicative of extensive cross-mating. This resource and generated data will be useful in determining regions important for adaptation to certain habitats.
Rights and permissions
About this article
Cite this article
Yeast pan-genome. Nat Methods 9, 326 (2012). https://doi.org/10.1038/nmeth.1953
Published:
Issue Date:
DOI: https://doi.org/10.1038/nmeth.1953