Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Cell Mechanics

Two regimes, maybe three?

We have begun to understand the physical determinants of cell rheology and their relevance to biological functions. Experiments performed on freshly excised cells offer a new perspective in which soft-glass rheology and prestress seem to play central roles.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: The cytoskeletal actin network of mouse embryonic fibroblasts.
Figure 2: What is relevant in cell rheology?

References

  1. Deng, L. et al. Nature Mater. 5, 636–640 (2006).

    Article  CAS  Google Scholar 

  2. Gardel, M. L. et al. Phys. Rev. Lett. 93, 188102 (2004).

    Article  CAS  Google Scholar 

  3. Lenormand, G. & Fredberg, J. J. Biorheology 43, 1–30 (2006).

    Google Scholar 

  4. Fabry, B. et al. Phys. Rev. Lett. 87, 14802 (2001).

    Article  Google Scholar 

  5. Bursac, P. et al. Nature Mater. 4, 558–561 (2005).

    Article  Google Scholar 

  6. Despart, N., Richert, A., Simeon, J. & Asnacios, A. Biophys. J. 88, 2224–2233 (2005).

    Article  Google Scholar 

  7. Overby, D. R., Matthews, B. D., Alsberg, E. & Ingber, D. E. Acta Biomater. 1, 295–303 (2005).

    Article  Google Scholar 

  8. Wang, N. et al. Proc. Natl. Acad. Sci. USA 98, 7765–7770 (2001).

    Article  CAS  Google Scholar 

  9. Stamenović, D., Suki, B., Fabry, B., Wang, N. & Fredberg, J. J. J. Appl. Physiol. 96, 1600–1605 (2004).

    Article  Google Scholar 

  10. Gardel, M. L. et al. Phys. Rev. Lett. 96, 088102 (2006).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Stamenović, D. Two regimes, maybe three?. Nature Mater 5, 597–598 (2006). https://doi.org/10.1038/nmat1700

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nmat1700

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing