Pancreatic ductal adenocarcinoma (PDAC) is characterized by an extensive stromal component that hinders treatment. A new study shows how the genetic identity of pancreatic tumors might influence the physical properties of the associated stroma to promote tumor progression.
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Rath, N., Olson, M. Regulation of pancreatic cancer aggressiveness by stromal stiffening. Nat Med 22, 462–463 (2016). https://doi.org/10.1038/nm.4099
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DOI: https://doi.org/10.1038/nm.4099
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