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A role for interleukin-22 in the alleviation of metabolic syndrome

Increasing evidence points to a role for the immune system in the regulation of metabolism. Two new studies in mice indicate treatment with interleukin-22 restores mucosal immunity in diabetes and alleviates metabolic disease, resulting in improved glycemic control.

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Figure 1: The effects of IL-22.

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Correspondence to Marc Y Donath.

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Dalmas, E., Donath, M. A role for interleukin-22 in the alleviation of metabolic syndrome. Nat Med 20, 1379–1381 (2014). https://doi.org/10.1038/nm.3748

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