This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Gamble JL (1947) Chemical anatomy, physiology and pathology of extracellular fluid; a lecture syllabus, edn 5. Cambridge: Harvard University Press
Emmett M and Narins RG (1977) Clinical use of the anion gap. Medicine (Baltimore) 56: 38–54
Oh MS and Carroll HJ (1977) The anion gap. N Engl J Med 297: 814–817
Winter SD et al. (1990) The fall of the serum anion gap. Arch Intern Med 150: 311–313
Narins RG and Emmett M (1980) Simple and mixed acid–base disorders: a practical approach. Medicine (Baltimore) 59: 161–187
Oster JR et al. (1988) Use of the anion gap in clinical medicine. South Med J 81: 229–237
Carlisle EJ et al. (1991) Glue-sniffing and distal renal tubular acidosis: sticking to the facts. J Am Soc Nephrol 1: 1019–1027
Figge J et al. (1998) Anion gap and hypoalbuminemia. Crit Care Med 26: 1807–1810
Corey HE (2003) Stewart and beyond: new models of acid–base balance. Kidney Int 64: 777–787
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The author declares no competing financial interests.
Rights and permissions
About this article
Cite this article
Emmett, M. Anion-gap interpretation: the old and the new. Nat Rev Nephrol 2, 4–5 (2006). https://doi.org/10.1038/ncpneph0073
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1038/ncpneph0073
This article is cited by
-
Association between albumin corrected anion gap and 30-day all-cause mortality of critically ill patients with acute myocardial infarction: a retrospective analysis based on the MIMIC-IV database
BMC Cardiovascular Disorders (2023)
-
Severe euglycemic diabetic ketoacidosis of multifactorial etiology in a type 2 diabetic patient treated with empagliflozin: case report and literature review
BMC Nephrology (2020)
-
Diabetic ketoacidosis
Nature Reviews Disease Primers (2020)
-
Treatment of acute metabolic acidosis: a pathophysiologic approach
Nature Reviews Nephrology (2012)