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Metalloproteins

A new face for biomass breakdown

Lytic polysaccharide mono-oxygenases oxidatively cleave the glycosidic chain on the crystalline surface of cellulose or chitin to create an entry point for hydrolytic cellulases or chitinases. The discovery of a new family of lytic polysaccharide mono-oxygenases expands the possibilities for the use of these enzymes to accelerate biomass degradation.

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Figure 1: Mode of action and structure of cellulolytic LPMOs.

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Correspondence to Shinya Fushinobu.

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Fushinobu, S. A new face for biomass breakdown. Nat Chem Biol 10, 88–89 (2014). https://doi.org/10.1038/nchembio.1434

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